成功大學統計學系

系所成員
姓名 詹世煌
職稱 退休副教授 / 109.02.01退休
專長領域 多變量分析、長期資料迴歸分析、生物資訊
E-mail shchan@ncku.edu.tw
辦公室 管理學院統計系館4樓62445室
個人網頁 https://researchoutput.ncku.edu.tw/zh/persons/shih-huang-chan
經 歷(Main Experiences)
  • 成功大學統計系副教授(1989.05-目前)
學歷(Education)
  • 美國俄亥俄州統計博士(1989)
研究方向(Research Field)
  • Longitudinal Data Analysis
  • Diagnostics On Outliers and Influential Observations
  • Genetic Linkage Analysis
  • Microarray Analysis
期刊論文
  1. Hepatitis B virus surface gene pre-S2 mutant as a high-risk serum marker for hepatoma recurrence after curative hepatic resection
    Yen, C., Ai, Y., Tsai, H., Chan, S., Yen, C., Cheng, K., Lee, Y., Kao, C., Wang, Y., Chen, Y., Lin, C., Liu, T., Tsai, H., Wang, J., Su, I. & Huang, W., 2018 九月 1, 於 : Hepatology. 68, 3, p. 815-826

  2. Hepatitis B virus surface gene pre-S2 mutant as a high-risk serum marker for hepatoma recurrence after curative hepatic resection
    Yen, C. J., Ai, Y. L., Tsai, H. W., Chan, S. H., Yen, C. S., Cheng, K. H., Lee, Y. P., Kao, C. W., Wang, Y. C., Chen, Y. L., Lin, C. H., Liu, T., Tsai, H. P., Wang, J. R., Su, I. J. & Huang, W., 2018 九月, 於 : Hepatology. 68, 3, p. 815-826 12 p.

  3. NEK2 promotes hepatoma metastasis and serves as biomarker for high recurrence risk after hepatic resection
    Chang, Y. Y., Yen, C. J., Chan, S. H., Chou, Y. W., Lee, Y. P., Bao, C. Y., Huang, C. J. & Huang, W., 2018 九月 1, 於 : Annals of Hepatology. 17, 5, p. 843-856 14 p.

  4. NEK2 Promotes Hepatoma Metastasis and Serves as Biomarker for High Recurrence Risk after Hepatic Resection
    Chang, Y., Yen, C., Chan, S., Chou, Y., Lee, Y., Bao, C., Huang, C. & Huang, W., 2018 八月 24, 於 : Annals of Hepatology. 17, 5, p. 843-856

  5. Progesterone receptor membrane component 1 as a potential prognostic biomarker for hepatocellular carcinoma
    Tsai, H. W., Ho, C. L., Cheng, S. W., Lin, Y. J., Chen, C. C., Cheng, P. N., Yen, C. J., Chang, T. T., Chiang, P. M., Chan, S. H., Ho, C. H., Chen, S. H., Wang, Y. W., Chow, N. H. & Lin, J. C., 2018 三月 14, 於 : World journal of gastroenterology. 24, 10, p. 1152-1166 15 p.

  6. Resistance of ground glass hepatocytes to oral antivirals in chronic hepatitis B patients and implication for the development of hepatocellular carcinoma
    Tsai, H. W., Lin, Y. J., Wu, H. C., Chang, T. T., Wu, I. C., Cheng, P. N., Yen, C. J., Chan, S. H., Huang, W. & Su, I. J., 2016 五月 10, 於 : Oncotarget. 7, 19, p. 27724-27734 11 p.

  7. Lin28B is an oncofetal circulating cancer stem cell-like marker associated with recurrence of hepatocellular carcinoma
    Cheng, S. W., Tsai, H. W., Lin, Y. J., Cheng, P. N., Chang, Y. C., Yen, C. J., Huang, H. P., Chuang, Y. P., Chang, T. T., Lee, C. T., Chao, A., Chou, C. Y., Chan, S. H., Chow, N. H. & Ho, C. L., 2013 十一月 14, 於 : PloS one. 8, 11, e80053.

  8. A clustered ground-glass hepatocyte pattern represents a new prognostic marker for the recurrence of hepatocellular carcinoma after surgery
    Tsai, H. W., Lin, Y. J., Lin, P. W., Wu, H. C., Hsu, K. H., Yen, C. J., Chan, S. H., Huang, W. & Su, I. J., 2011 七月 1, 於 : Cancer. 117, 13, p. 2951-2960 10 p.

  9. A robust ratio estimator of gene expression via inverse-variance weighting for cDNA microarray images
    Chan, S. H. & Chang, W. C., 2009 三月 15, 於 : Computational Statistics and Data Analysis. 53, 5, p. 1577-1589 13 p.

  10. Prohibitin in the pathogenesis of transitional cell bladder cancer
    Wu, T. F., Wu, H., Wang, Y. W., Chang, T. Y., Chan, S. H., Lin, Y. P., Liu, H-S. & Chow, N. H., 2007 三月 1, 於 : Anticancer Research. 27, 2, p. 895-900 6 p.

  11. Genetic polymorphisms in CYP1A1 and GSTM1 predispose humans to PCBs/PCDFs-induced skin lesions
    Tsai, P. C., Huang, W-Y., Lee, Y. C., Chan, S-H. & Guo, Y. L., 2006 五月 1, 於 : Chemosphere. 63, 8, p. 1410-1418 9 p.

  12. The significance of prohibitin and c-Met/hepatocyte growth factor receptor in the progression of cervical adenocarcinoma
    Tsai, H. W., Chow, N. H., Lin, C. P., Chan, S. H., Chou, C. Y. & Ho, C. L., 2006 二月 1, 於 : Human Pathology. 37, 2, p. 198-204 7 p.

  13. An ancova approach to normalize microarray data, and its performance to existing methods
    Chan, S. H., Chen, L. J., Chow, N. H. & Liu, H. S., 2005 四月 1, 於 : Journal of Bioinformatics and Computational Biology. 3, 2, p. 257-268 12 p.

  14. Nasopharyngeal carcinoma-susceptibility locus is localized to a 132 kb segment containing HLA-A using high-resolution microsatellite mapping
    Lu, C-C., Chen, J. C., Tsai, S-T., Jin, Y. T., Tsai, J-C., Chan, S-H. & Su, I. J., 2005 七月 10, 於 : International Journal of Cancer. 115, 5, p. 742-746 5 p.

  15. Clinical significance of allelotype profiling for urothelial carcinoma
    Tzai, T. S., Chen, H. H. W., Chan, S. H., Ho, C. L., Tsai, Y. S., Cheng, H. L., Dai, Y. C., Lin, J. S. N., Yang, W. H. & Chow, N. H., 2003 八月 1, 於 : Urology. 62, 2, p. 378-384 7 p.

  16. Genetic susceptibility to nasopharyngeal carcinoma within the HLA-A locus in Taiwanese
    Lu, C. C., Chen, J. C., Jin, Y. T., Yang, H. B., Chan, S. H. & Tsai, S. T., 2003 三月 1, 於 : International Journal of Cancer. 103, 6, p. 745-751 7 p.

  17. Overexpression of c-met as a prognostic indicator for transitional cell carcinoma of the urinary bladder: A comparison with p53 nuclear accumulation
    Cheng, H. L., Trink, B., Tzai, T. S., Liu, H. S., Chan, S. H., Ho, C. L., Sidransky, D. & Chow, N. H., 2002 三月 15, 於 : Journal of Clinical Oncology. 20, 6, p. 1544-1550 7 p.

  18. Education and cognitive decline in parkinson's disease: A study of 102 patients
    Pai, M. C. & Chan, S. H., 2001 四月 26, 於 : Acta Neurologica Scandinavica. 103, 4, p. 243-247 5 p.

  19. Expression profiles of ErbB family receptors and prognosis in primary transitional cell carcinoma of the urinary bladder
    Chow, N-H., Chan, S-H., Tzai, T. S., Ho, C-L. & Liu, H-S., 2001 十一月 6, 於 : Clinical Cancer Research. 7, 7, p. 1957-1962 6 p.

  20. The clinical value of p21(WAF1/CIP1) expression in superficial bladder cancer
    Chow, N-H., Tzai, T. S., Cheng, H-L., Liu, H-S., Chan, S-H. & Tong, Y-C., 2000 一月 1, 於 : Anticancer Research. 20, 2 B, p. 1173-1176 4 p.

  21. The role of nm23-H1 in the progression of transitional cell bladder cancer
    Chow, N-H., Liu, H-S. & Chan, S-H., 2000 九月 26, 於 : Clinical Cancer Research. 6, 9, p. 3595-3599 5 p.

  22. Expression of vascular endothelial growth factor in primary superficial bladder cancer
    Chow, N. H., Liu, H. S., Chan, S. H., Cheng, H. L. & Tzai, T. S., 1999 十二月 1, 於 : Anticancer research. 19, 5 C, p. 4593-4597 5 p.

  23. The role of bcl-2 in the progression of the colorectal adenoma-carcinoma sequence
    Yang, H. B., Chow, N-H., Sheu, B-S., Chan, S-H., Chien, C. H. & Su, I. J., 1999 四月 20, 於 : Anticancer research. 19, 1 B, p. 727-730 4 p.

  24. Expression of fibroblast growth factor-1 and fibroblast growth factor-2 in normal liver and hepatocellular carcinoma
    Chow, N. H., Cheng, K. S., Lin, P. W., Chan, S. H., Su, W. C., Sun, Y. N. & Lin, X. Z., 1998 十一月 5, 於 : Digestive Diseases and Sciences. 43, 10, p. 2261-2266 6 p.

  25. Effect of Thyroid Hormone on Urinary Excretion of Epidermal Growth Factor
    Huang, S. M., Chan, S. H., Wu, T. J. & Chow, N. H., 1997 一月 1, 於 : European Surgical Research. 29, 3, p. 222-228 7 p.

  26. Expression of vascular endothelial growth factor in normal liver and hepatocellular carcinoma: An immunohistochemical study
    Chow, N. H., Hsu, P. I., Lin, X. Z., Yang, H. B., Chan, S. H., Cheng, K. S., Huang, S. M. & Su, I. J., 1997 一月 1, 於 : Human Pathology. 28, 6, p. 698-703 6 p.

  27. Expression patterns of erbB receptor family in normal urothelium and transitional cell carcinoma. An immunohistochemical study
    Chow, N-H., Liu, H-S., Yang, H. B., Chan, S-H. & Su, I. J., 1997 八月 14, 於 : Virchows Archiv. 430, 6, p. 461-466 6 p.

  28. Implications of serum basic fibroblast growth factor levels in chronic liver diseases and hepatocellular carcinoma
    Hsu, P. I., Chow, N-H., Lai, K. H., Yang, H. B., Chan, S-H., Lin, X-Z., Cheng, J. S., Huang, J. S., Ger, L. P., Huang, S-M., Yen, M. Y. & Yang, Y. F., 1997 九月 3, 於 : Anticancer Research. 17, 4 A, p. 2803-2809 7 p.

  29. Prognostic significance of proliferating cell nuclear antigen expression in transitional cell carcinoma of the upper urinary tract
    Cheng, H-L., Chow, N-H., Tzai, T. S., Tong, Y-C., Lin, J. S. N., Chan, S-H., Yang, W-H., Chang, C. C. & Lin, Y., 1997 九月 3, 於 : Anticancer Research. 17, 4 A, p. 2789-2793 5 p.

  30. Significance of urinary epidermal growth factor and its receptor expression in human bladder cancer
    Chow, N. H., Liu, H. S., Lee, E. I. C., Chang, C. J., Chan, S. H., Cheng, H. L., Tzai, T. S. & Lin, J. S. N., 1997 十二月 1, 於 : Anticancer research. 17, 2B, p. 1293-1296 4 p.

  31. Clinical presentation and prognostic factors in sodium monofluoroacetate intoxication
    Chi, C-H., Chen, K. W., Chan, S-H., Wu, M. H. & Huang, J. J., 1996 一月 1, 於 : Journal of Toxicology - Clinical Toxicology. 34, 6, p. 707-712 6 p.

  32. Growth kinetics of colorectal adenoma-carcinoma sequence: An immunohistochemical study of proliferating cell nuclear antigen expression
    Yang, H. B., Hsu, P. I., Chan, S. H., Lee, J. C., Shin, J. S. & Chow, N. H., 1996 一月 1, 於 : Human Pathology. 27, 10, p. 1071-1076 6 p.

  33. Implications of urinary basic fibroblast growth factor excretion in patients with urothelial carcinoma
    Chow, N-H., Chang, C-J., Yeh, T-M., Chan, S-H., Tzai, T. S. & Lin, J. S. N., 1996 一月 1, 於 : Clinical Science. 90, 2, p. 127-133 7 p.

  34. Adenoma‐carcinoma sequence: A reappraisal with immunohistochemical expression of ferritin
    Yang, HB. B., Hsu, PI. I., Lee, JC. C., Chan, SH. H., Lin, XZ. Z. & Chow, NH. H., 1995 九月, 於 : Journal of Surgical Oncology. 60, 1, p. 35-40 6 p.

  35. Prognostic significance of ferritin expression in colorectal adenocarcinoma
    Hsu, P. I., Chow, N-H., Lin, X-Z., Yang, H. B., Chan, S-H. & Lee, P. C., 1995 一月 1, 於 : Anticancer Research. 15, 3, p. 1087-1093 7 p.

  36. Significance of urinary tissue polypeptide specific antigen (TPS). Determination in patients with urothelial carcinoma
    Yao, W-J., Chang, C-J., Chan, S-H., Chow, N-H., Cheng, H-L., Tzai, T. S. & Lin, S. N., 1995 十二月 1, 於 : Anticancer research. 15, 6 B, p. 2819-2823 5 p.

  37. Bleeding peptic ulcer - Risk factors for rebleeding and sequential changes in endoscopic findings
    Hsu, P. I., Lin, X. Z., Chan, S. H., Lin, C. Y., Chang, T. T., Shin, J. S., Hsu, L. Y., Yang, C. C. & Chen, K. W., 1994 六月, 於 : Gut. 35, 6, p. 746-749 4 p.

  38. Urinary cytodiagnosis: Can it have a different prognostic implication than a diagnostic test?
    Chow, N-H., Tzai, T. S., Cheng, H-L., Chan, S-H. & Lin, J. S. N., 1994 一月 1, 於 : Urologia Internationalis. 53, 1, p. 18-23 6 p.

  39. Reappraisal of the biological role of epidermal growth factor receptor in transitional cell carcinoma
    Chow, N. H., Tzai, T. S., Lin, S. N., Chan, S. H. & Tang, M. J., 1993 一月 1, 於 : European Urology. 24, 1, p. 140-143 4 p.

  40. On the calculations of the maximum likelihood estimates for the polynomial spline regression model with unknown knots and ar(1) errors
    Chan, S-H., 1991 一月 1, 於 : Communications in Statistics - Theory and Methods. 20, 4, p. 1199-1209 11 p.

獎勵榮譽
  • 98學年度榮獲成功大學-校優良導師